The typical content of gamma-linolenic acid (GLA) in the oil is 8% to 10%. Also known as "king's cure-all" or "night willow herb," evening primrose is a wildflower with medicinal properties. This information should not be used to decide whether or not to take this product. If you are among those people, always consider the size of the evening primrose oil capsule. Originating from North America, evening primrose is a flowering, yellow plant traditionally used to heal bruises and treat a variety of skin conditions. For those who are new to aromatherapy, you may be wondering what is evening primrose oil? This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This is only a brief summary of general information about this product. Most health stores sell dietary supplements containing evening primrose oil (EPO), which is extracted from the plant's seeds. Evening primrose oil was previously suspected to lower the seizure threshold in schizophrenic patients; however, this is now disputed. Evening Primrose Oil. Due to the lack of research, evening primrose should be not be used in children. Used as recommended, EPO is generally considered safe. Mild self-limiting nausea was reported in 2 women in the intervention group.68. When taken by mouth, it can sometimes cause mild side effects including upset stomach, nausea, diarrhea, and headache. Consider therapy modification.59, 60, 61, 62, Herbs (anticoagulant/antiplatelet properties): Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of other herbs (anticoagulant/antiplatelet properties). Side effects of supplementing with evening primrose oil include headaches and mild stomach upset (diarrhoea or nausea). – Different conditions require different dosages. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Clinical trials are lacking.56, A Cochrane review of randomized trials comparing evening primrose oil with placebo suggests some benefit in using evening primrose oil for rheumatoid arthritis, despite the relative poor quality of the individual studies. . 1. It is used for its natural healing properties. Generally speaking, a daily dose of 500 milligrams is considered safe in adults, although many can tolerate up to 1,300 milligrams daily without any side effects. This information is not specific medical advice and does not replace information you receive from your health care provider. To moisturise skin or hair, you’ll want to use oil – or a product containing the oil – directly on your skin/hair. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This Mediterranean-style approach to eating may improve glycemic control and cardiovascular disease risk factors (moderate-quality evidence).69, Current interest in the use of evening primrose oil for enhancing intellectual performance in children is yet to be validated by rigorous research. Evidence suggests that evening primrose oil may be effective for treating rheumatoid arthritis, injection site skin reactions, and diabetic neuropathy, but is lacking to support its place in the treatment of atopic eczema/dermatitis syndrome, menopausal vasomotor symptoms, mastalgia, or multiple sclerosis. Meta-analyses conducted with 7 studies using participant-reported improvements (n = 176) and 8 using physician-assessed improvements (n = 289) support previous reports of the lack of effectiveness of evening primrose oil.67, While an older review suggested promising results12 the most comprehensive meta-analysis to date did not establish efficacy.10 Clinical studies continue to be conducted, with a gradual time-dependent improvement suggested.13, There is no recent evidence to support older studies38, 39, 40 suggesting that evening primrose oil reduced platelet aggregation. Modern medicine uses the oil extract from evening primrose seeds in supplements to treat eczema, breast pain, and menopausal symptoms. F… What works for you may not be the best for another. Starting around 37 weeks insert 1 capsule (500 mg) vaginally every evening before going to bed. It is commonly used for eczema and skin disorders in both human beings and animals. It may take up to six months until you see noticeable results. Also known as "king's cure-all" or "night willow herb," evening primrose is a wildflower with medicinal properties. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In some cases, the dose could be increased to 1-3  capsules per day (no more than 3000mg). Some of the many benefits of evening primrose oil include its ability to soothe inflammation, strengthen the bones, promote good skin health, balance hormones, lower cholesterol, optimize digestion, regulate blood sugar levels, prevent hair loss, ease pain and aid in weight loss efforts. What Are The Best Essential Oils For Nail Fungus? 2000;(1):CD002947. Evening primrose oil side effects Quantitative Insulin Check Index (P=0.007) was found to be significantly different between groups.70, Topical application of saponified evening primrose oil reduced ultraviolet B-induced hyperpigmentation, while a decrease in melanin production has been demonstrated in vivo with the saponified oil.54, Local injection-site reactions after subcutaneous injections of 5-azacitidine and bortezomib have been reduced with topical application of evening primrose oil.55, 66 Additionally, the time to complete resolution of bortezomib-induced skin reactions was shortened (median, 4 days).66, There is little evidence to support the efficacy of evening primrose oil in treatment of mastalgia, with most trials finding no advantage over placebo.14, 15, 16, 17 Although 23% taking evening primrose oil experienced a complete response in a small randomized, comparator trial (n = 135) after 6 months of therapy, this response was statistically significantly less than the group receiving the study drug Centchroman, a novel nonsteroidal selective anti-estrogen oral contraceptive, which showed an 86% response (P < 0.05).65 A meta-analysis of clinical trials found no evidence of effect in pain relief, with a mean pain score difference of -2.78 (95% confidence interval, -7.97 to 2.4).18, A number of reviews and randomized clinical trials found no evidence of benefit with evening primrose oil use for menopausal vasomotor symptoms or premenstrual syndrome.19, 20, 21, 22, 23, 24, 25 In 2004, the North American Menopause Society did not support the use of evening primrose oil for menopausal vasomotor symptoms given the lack of efficacy data, but this has not been recently reviewed.26 The Society of Obstetricians and Gynaecologists of Canada revised clinical practice guidelines (2014) on managing menopause do not recommend evening primrose oil for reducing menopausal symptoms based on a lack of evidence to support clinical benefit.71 A 2013 randomized, double-blind, placebo-controlled trial in 56 menopausal treatment-naïve Iranian women (with at least 4 hot flashes a day) documented significant changes from baseline for hot flash severity, but not in their frequency or duration, in those randomized to receive 1,000 mg/day evening primrose oil extract for 6 weeks. Evening primrose oil is a herbal supplement that comes from the evening primrose plant. Side effects, drug interactions, dosage, storage, and safety information should be reviewed prior to taking this supplement. 10 Best Evening Primrose Oil Supplements – Dosage and benefits, Cabbage Soup Detox for Weight Loss: 7-Day Diet Plan. The GLA in EPO is thought to help acne by reducing skin inflammation … Recommended dosage Evening primrose oil can be obtained in health food stores in either liquid or capsule form. Evening primrose oil acne dosage equals to 1000mg daily. The most common side effects are temporary gastrointestinal symptoms such as abdominal pain, fullness, or nausea. Like the article said, the dose should be broken up into two or three doses. We comply with the HONcode standard for trustworthy health information -. Wild varieties of O. biennis contain highly variable amounts of linoleic acid and GLA; however, extensive crossbreeding has produced a commercial variety that consistently yields oil with 72% cis-linoleic acid and 9% GLA.2, 3 Also found are cis-6,9,12-octadecatrienoic acid; small amounts of oleic, palmitic, and stearic acids; steroids; campesterol; and beta-sitosterol. Evening Primrose Oil for Oily Skin: Stop That Shine! We use cookies to ensure that we give you the best experience on our website. The 500mg capsule is twice as small as the 1000mg capsule. With high amounts of natural omega-6 fatty acids, linoleic acid, and gamma-linolenic acid (GLA), evening primrose oil inhibits the body's natural production of the chemicals which generally cause inflammation on the skin as well as in the joints. If the supplement is taken in liquid form, then obviously the doses are different. This website is strictly for the purpose of providing opinions of the author. Usually, mild side effects like headache, nausea, upset stomach and loose stools, are experienced by some of the users. Evening primrose oil is a herbal supplement that comes from the evening primrose plant. Changes in mean weight (P=0.75), body mass index (P=0.52), and HDL-cholesterol (P=0.13) were not found to be significantly different between groups. This oil has a number of medicinal uses and hence, is widely used in the management of several disorders. Look for high-quality evening primrose oil certified as organic by a reputable third party. Special Precautions & Warnings: Pregnancy and breast-feeding: Taking evening primrose by mouth is POSSIBLY SAFE during pregnancy. The normal dose for evening primrose oil is 1000mg to 3000mg/day. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. Side Effects of Evening Primrose Oil. Always take evening primrose supplements with your meal. Recommended Evening Primrose Oil Dosage. Additionally, 3 Hot Flash Related Daily Interference Scale subscores improved significantly: social activity, relations with others, and sexuality. Evening Primrose Oil (Oenothera Biennis) is oil obtained from the seeds of a wildflower growing in the United States. As a dietary supplement, there are no universal guidelines directing the appropriate use of evening primrose oil. The supplement contains the fatty acid gamma-linolenic acid (GLA).People take evening primrose oil orally to treat a wide variety of conditions. Early research shows that taking 6 grams of evening primrose oil per day for 10 weeks may reduce finger and toe sores in people with this condition. A range of evening primrose oil products are available for purchase online. The use of Evening Primrose Oil is beneficial in the management of eczema. The use of Evening Primrose Oil … Few adverse effects were noted in these trials, and there was no increase in blood glucose levels.43, 44, As a component of medical nutrition therapy for patients with type 2 diabetes, the American Diabetes Association Standards of Care (2014) recommends higher quality dietary fat intake, as an alternative to decreased fat intake, by replacing saturated and/or trans fats with mono- and poly-unsaturated fatty acids in the diet. Medscape - Indication-specific dosing for fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop (evening primrose oil), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. These two acids are thought to be the healing ingredients in EPO. 1,3 Today, this oil is commonly used as a carrier oil for essential oils but carries its own benefits, as well. Vitamin E is a fat-soluble antioxidant known for its ability to build and repair tissues . Evening primrose is not considered to be safe if used in pregnancy. It may take up to six months until you see noticeable results. Get the best articles straight into your inbox before everyone else! Consider therapy modification.59, 60, 61, 62, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. For weight loss purposes take 3000-5000 mg of EPO daily. Any and all trademarks, logos brand names and service marks displayed on this website are the registered or unregistered Trademarks of their respective owners. Best Natural Supplements and Vitamins for PCOS, DIY Vitamin C Serum – 3 Easy Homemade Recipes, Benefits of Rhodiola Rosea for Anxiety and Stress, Spirulina Face Mask: DIY Cleansing and Lifting Recipes, The Best Foot Soaks For Toenail Fungus (including DIY recipes), Top 6 Essential Oils for Nausea and Motion Sickness, 10 Spirulina Recipes That Are Actually Tasty, Evening primrose oil for menopause – reviews, dosage, and effects, What you need to know before taking Evening primrose oil to induce labor naturally, Evening Primrose Oil for Acne: “Before & After”. 1,300 mg . Evening Primrose Oil Side Effects. GNC Women's Evening Primrose Oil 1300mg: Supports hormonal balance, healthy skin and cardiovascular health. Here you'll find all collections you've created before. EPO capsules (500–1,300 mg) or oil (150 ml) are available from high-street retailers. Cochrane Database Syst Rev . When taken by mouth, it can sometimes cause mild side effects including upset stomach, nausea, diarrhea, and headache. Hot Side effects, drug interactions, dosage, storage, and safety information should be reviewed prior to taking this supplement. If you continue to use this site we will assume that you are happy with it. In vitro and in vivo animal studies suggest inhibition of platelet function in the newborn may have been caused by exposure to evening primrose oil.58, Agents with antiplatelet roperties: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of agents with antiplatelet properties. Bleeding may occur. Warnings. Whether you’re looking for Evening Primrose Oil capsules, Evening Primrose Oil with Cod Liver Oil, or a more general omega fatty acid health supplement, you’ll find it here. This oil contains a fatty acid called gamma-linolenic acid, or GLA for short, as well as linoleic acid. Minimize Breast Pain. Bleeding may occur. Evening Primrose Oil Side Effects and Dosage. Taking EPO may help to relieve breast pain. The recommended dose of evening primrose oil is 8 to 12 capsules a day, at a dose of 500 milligrams per capsule. Evening Primrose Oil Side Effects. The recommended evening primrose oil dosage is 1-6 capsules a day, at a dose of 500 milligrams per capsule. The 1300mg capsule would be even bigger than the 1000mg capsule of evening primrose oil. In cancer studies, … Evening primrose oil for eczema: no more itch? The basic side effects of evening primrose are rare and include the mild cases of stomach pain, headaches, nausea, and diarrhea. Generally, it is between 500- 1000 milligrams daily, often split up into smaller doses. For rheumatoid arthritis take 540 mg (one capsule of 500mg) daily to 2800mg (5-6 capsules of 500mg) daily in divided doses. Evening primrose oil has been administered orally in clinical trials at doses between 6 and 8 g/day in adults and 2 and 4 g/day in children. 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